Bk6 tcr
WebThe ectopic, left-sided TCR footprint of BK6 did not contact lipid antigens positioned within or on the right side of the CD1a platform, explaining the observed low specificity for differing CD1a ... WebThis kind of lipid-induced molecular arrangement was previously proposed to negatively impact the recognition of CD1a by the BK6 TCR and illustrates the situation in which an inhibitory ligand...
Bk6 tcr
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WebCD1a ternary complex with lysophosphatidylcholine and BK6 TCR Coordinates PDB Format Method Oligo State hetero-1-1-1-1-mer Ligands 1 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose (Post Translational Modification) 1 x 42H: (4R,7R,18Z)-4,7 ... WebStructure 4X6C CD1a ternary complex with lysophosphatidylcholine and BK6 TCR Assembly Asm Id 1: Author Defined Assembly Dynamic Bonds Off Nothing Focused …
WebAnti-Lysophosphatidylcholine TCR (clone BK6), Jurkat Cell Line (TCRJ-CQ017) All products and services are For Research Use Only and CANNOT be used in the treatment or … WebSep 21, 2015 · The natural killer T (NKT) cell TCR interacts with CD1d displaying α-galactosylceramide (αGalCer); the mucosal-associated invariant T (MAIT) cell TCR interacts with MHC class I-related protein...
WebThe BK6 TCR bound to mammalian CD1a-endo with an affinity (dissociation constant) of 29 µM (Fig. 3c-e), and we obtained a similar value for insect-derived CD1a-endo (data not … WebFeb 2, 2015 · The BK6 TCR–CD1a complex and unbound CD1a were purified by mixture of equal amounts of soluble CD1a and the BK6 TCR (24.5 μM) and by passage over a … Supplementary Figure 5 CD1a-sulfatide Tetramer Staining of Jurkat.BK6 Cells - … Supplementary Figure 1 Bk6 TCR Variable Sequence and Sds-Page From Size … Supplementary Figure 6 Collision-induced Dissociation (Cid-Ms) Analysis of Lipids … Submit Manuscript - αβ T cell antigen receptor recognition of CD1a presenting … Nature Immunology is a multidisciplinary journal that publishes papers of the …
WebJul 5, 2024 · Briefly, both chains of each TCR (BK6, CO3, CO22) separated by the self-cleaving peptide P2A were cloned in the shuttle vector pLV-EF1a-MCS-IRES-GFP …
WebAug 1, 2024 · Birkinshaw et al. studied that a prototypical autoreactive BK6 TCR bound CD1a when the presented ligands were permissive. TCR docked over the A’ roof of CD1a and a central CD1a salt-bridge network (Arg76-Glu154 salt-bridge) prevented the interaction between BK6 TCR and permissive ligands, and its autoreactivity was determined by … theory-based evaluationWeb4X6B BK6 TCR apo structure Assembly Asm Id 1: Author And Software Defined Assembly Dynamic Bonds Off Nothing Focused Measurements Structure Motif Search … theory-based ecologyWebmutoh日本mutoh编码器、mutoh旋转编码器、mutoh线性传感器日本mutoh（武藤）公司主要生产mutoh线... theory bar rescueWebNational Center for Biotechnology Information theory bar \u0026 moreWebDec 7, 2014 · 4X6B, 4X6C, 4X6D, 4X6E, 4X6F. PubMed Abstract: A central paradigm in αβ T cell-mediated immunity is the simultaneous co-recognition of antigens and antigen … theory-based approachWebTCR contact with hydrophilic head groups Most CD1 ligands are amphipathic lipids that carry polar or charged head groups comprised of one or more carbohydrate units, a peptide, a sulfate ester, or a phosphate ester. Typically, the polar and rigid head groups are not fully inserted into the CD1 cavity. theory based approach statisticsWebDec 8, 2014 · 4X6B, 4X6C, 4X6D, 4X6E, 4X6F. PubMed Abstract: A central paradigm in αβ T cell-mediated immunity is the simultaneous co-recognition of antigens and antigen … theory barrier