Glutathione s-transferase mu 4
WebMay 1, 2024 · The glutathione S-transferases (GST; EC 2.5.1.18) are a family of enzymes responsible for the metabolism of a broad range of xenobiotics and carcinogens ( Mannervik, 1985 ). This enzyme catalyzes the reaction of glutathione with a wide variety of organic compounds to form thioethers, a reaction that is sometimes a first step in a … WebJul 22, 2014 · Besides exhibiting antiproliferation action, butyrate also exhibits an antioxidant effect by augmenting cellular glutathione (GSH), reducing reactive oxygen species …
Glutathione s-transferase mu 4
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WebAbstract. Human glutathione S-transferases (GSTs) are a functionally diverse family of soluble enzymes of detoxification that use reduced glutathione (GSH) in conjugation and reduction reactions. Toxic electrophiles, including a variety of carcinogens, are substrates for the GSTs and after conjugation or reduction they are more easily excreted ... WebMay 1, 2024 · 138333 - GLUTATHIONE S-TRANSFERASE, MU-4; GSTM4 - GLUTATHIONE S-TRANSFERASE M4 - GSTM4 Ross and Board (1993) cloned and characterized GSTM4. Ross et al. (1993) reported that a probe derived from GSTM4 cross-hybridized with the other 3 known human mu class GST genes: GSTM1, GSTM2 …
WebJun 15, 2024 · The Glutathione S-transferase Mu (GSTM) has five members, including GSTM1-5. These GSTMs is involved in cell metabolism and detoxification, but their role in OC remains unknown. WebMay 1, 2024 · The glutathione S-transferases (GST; EC 2.5.1.18) are a family of enzymes responsible for the metabolism of a broad range of xenobiotics and carcinogens …
WebNov 1, 2024 · Regarding the detoxification pathways of platinum derivatives as well as paclitaxel, as the drugs most commonly used to treat metastatic ovarian cancer patients, glutathione transferases (GSTs) have been recognized as the major enzymes responsible for the conversion of these drugs into less effective forms [28]. WebGlutathione S-transferases (GST) comprise a family of enzymes which are critical for inactivation of toxins and carcinogens. We examined the cellular expression of multiple subclasses of GST immunohistochemically in 25 radical prostatectomy specimens with clinically localized prostate cancer. Gleaso …
WebIntroduction. A number of pro-oxidant air pollutants, including particulate matter, tobacco smoke, diesel exhaust and ozone (O 3) have been linked to exacerbation of asthma and …
WebGlutathione S-transferase (GST) is a kind of multifunctional supergene family enzymes, widely distributed in mammals, birds, insects, ... The LOD and LOQ of GST was lower to be 0.19 mU·L −1 and 0.57 mU·L −1. The relative standard deviations at different concentrations in three replicates for GST detection are lower than 3.85% ... metals can be s meaning that it ringsWebAt present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta, and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including ... metal scapular catholic nearbyWeb3.2 Glutathione S-transferases. Glutathione S-transferase (GST) is a major enzyme among phase II detoxification enzymes mainly present in the cytosol. ... The alpha, mu, … metal scarecrow garden stakeWebProtein target information for Glutathione S-transferase Mu 4 (human). Find diseases associated with this biological target and compounds tested against it in bioassay … how to abbreviate the word weightWebGlutathione S-transferase Mu 5. Gene. Gstm5. Status. UniProtKB reviewed (Swiss-Prot) Organism. Mus musculus (Mouse) Amino acids. 224. Protein existence. Evidence at protein level. Annotation score. 5/5. ... SFLDS00019 Glutathione_Transferase_(cytos 1 hit; SUPFAM. SSF47616 GST C-terminal domain-like 1 hit; metals channel global mining titans indexWebGSTM4 (glutathione S-transferase mu 4) haplotype 1101000 may be an important determinant for lung function growth; Observational study of gene-disease … how to abbreviate the year 2000WebGlutathione S-transferase Mu 4 is an enzyme that in humans is encoded by the GSTM4 gene. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega ... how to abbreviate the word with